Wednesday, 11 November 2015

DMSP-degrading bacteria - In control of Corals


Dimethylsulfoniopropionate (DMSP) is an organic sulfur molecule known for its role in climate regulation. Previous studies have shown that zooxanthellae (genus Symbiodinium) abundance found in cnidarian species are correlated to DMSP concentrations among the host, which are further available for coral-associated bacteria that metabolize it into dimethylsulfide (DMS) – the gas implicated in climate regulation. Two DMSP degradation pathways may occur, one involving phytoplankton or bacteria using enzymes (DMSP lyases) and the other involving only bacteria which carry out an initial demethylation of DMSP to methylmercaptopropionate (MMPA). This initial step involves a single gene, DMSP demethylase (dmdA). DMSP has been thought to act as an antioxidant towards marine algae, helping corals survive periods of thermal stress. Mucus-associated microbes have also been seen to play an important role in protecting the host coral against pathogens. The surface mucus is also subjected to high levels of DMSP which leaks from coral tissues. Furthermore, there is a possibility for DMSP degradation to take place in the surface mucus layer in corals, where coral associated DMSP-demethylating microbial communities perform this. 

This study by Frade et al. (2015) looks at the link between coral DMSP availability and the community dynamics of DMSP-demethylating bacteria found in the surface mucus of corals. This was done by first determining in situ DMSP concentrations in the tissue of three common reef-building coral species (Meandrina meandrites, Porites astreoides and Siderastrea sidereal) in relation to solar radiation intensity and desiccation stress (exposure to air). Genetic analysis was used to investigate taxonomic affiliation and relative abundance of mucus-associated bacterial assemblages harboring the gene dmdA

The results showed that DMSP varied with host species-specific traits such as zooxanthellae cell abundance. It was mostly seen that the occurrence of higher symbiont cell abundance as a cause for increased amounts of DMSP in the tissue. Exposure to air caused a doubling of their DMSP concentration, suggesting rapid de novo production of DMSP by the coral symbiont, either by the zooxanthellae or the coral host itself, possibly due to oxidative stress from thermal stress which further suggests the molecules role as an antioxidant. A higher availability of DMSP corresponded to a lower relative abundance of the dmdA gene, however this was not seen throughout all host species suggesting distinct DMSP microbial niches exist. 

Overall, this study is the first to provide quantification of dmdA gene assemblages in corals and link it to changes in community dynamics of DMSP-degrading bacteria to DMSP availability. It shows that DMSP is important in establishing links between coral hosts and associated bacterial communities, with the possibility of shifts in these communities and growth rates to depend on DMSP availability. Further study should be done into correcting the assumptions (such as whether changes in the relative abundance of dmdA genes relate to the degree of adaptation) which may allow a more definitive answer behind this study. 


Frade, P. R. et al., 2015. Dimethylsulfoniopropionate in corals and its interrelations with bacterial assemblages in coral surface mucus. Environmental Chemistry, pp. A-K.

2 comments:

  1. Given what we discussed from today's seminar (17th), do you think that the increased production of DMSP may be due to the increased chances of Vibrios and other opportunistic pathogens infecting the coral, as well as a response to thermal stress? Were any pathogens discussed in this paper?

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  2. The conclusion of this paper states that DMSP mediates the regulation of microbes by the coral host, which goes against obviously what we talked about in the seminar on the 17th, how increased DMSP may lead to increased Vibrios. They did not talk about Pathogens in the paper, they only mentioned the phylogenetic affiliation of bacterial dmdA gene (Demethylase gene) assemblages, which showed that the gene was affiliated to Alphaproteobacteria closely. Because they only looked at bacteria associated with this gene and it's role in demethylising DMSP, I do believe further study should be taken in looking at including the coral holobiont. Relying solely on looking at this gene dmdA only provides one side of answers, rather than what other consequences of increase DMSP could lead to.

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